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Exonic

Unsupervised Biological AI

y-combinatorFall 2025🇺🇸 San Francisco3 peoplehiring
Ben Brimacombe

Ben Brimacombe · 1 founder

2025Founded
Team
3
current
Co-founders
1
current
Stage
Founded
Source for Founded
Profile coverage4 of 8 · missing Funding, Signals, Customers, Stack / tools · last run 8/8/2026

About

What if you could train a biological foundation model on... the entire internet? Exonic is pioneering a new generation of biological foundation models, focused on heterogeneous, unstructured, and noisy datasets. Our first application is the design of safer gene therapies. In 2025, we used AI to set a new state of the art in liver cancer targeted gene therapy, validated in vitro in our lab in San Francisco. So far in 2026, we have trained a new model with unprecedented zero-shot generalization on genomic regulatory expression in hold-out biosample datasets. More to be shared soon.

Founder